Can anybody tell me what affects they encountered during Fertility Drug Treatments?… by C

April 24, 2007 · Filed Under gonal-f · Comment 

I am thinking about donating an ovum to a friend who cannot conceive and I would have to go through a month of Fertility Drugs (injections). I would like info from people who have gone through the drugs. Thanks!


Best Answer:


I have done clomid and 2 rounds of injectible medications (Gonal-F and Menopur). The injectible meds were not bad. The stim drugs come with a really fine gauge needle, so the shots weren't painful. Sometimes, the injection site would sting a bit and get a raised bump.

My ovaries felt very full, and it became uncomfortable to bend over after a week of taking the shots. I did get ovarian hypersimulation (OHSS) the first time, as I was pretty young(29) and I responded very quickly to the meds. My main symptoms were ovarian tenderness and a little nausea for about 5- 6 days. Some women get it worse, and may have to be hospitalized if it is bad.

I was a little moodier than usual with the meds, like mild PMS. But actually, clomid effected me much worse than any of the injectible meds did.

The egg retrieval is a little scary, especially when you see the big needle they are going to suck the eggs out with! Many women get lots of sedation and can't remember the procedure, even though it is a waking anesthesia they give you. I had twilight sedation, but it didn't work too well as I remember all of the details clearly. It was a small bit painful as I had 33 eggs retrieved, but it was nothing awful at all.

I think it is wonderful that you are considering doing such a nice thing for a friend. It really is usually pretty painless for most women, especially when you think about how significant the results of a little discomfort can be in the long run. Also, please remember that usually when a woman is on these drugs, she is doing it because she is infertile and trying to conceive her own baby. This stress can add a lot of emotional baggage to a cycle that will not be there for you. Some things like weight gain and relationship problems are more likely due to this stress than the meds themselves. Good luck!
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What is the plant base of the anti-malaria drug chloroquine?… by Kyl

April 23, 2007 · Filed Under chloroquine · Comment 

I am trying to figure out where the drug chloroquine comes from? Is it plant based, or completely, chemically engineered?

If you can find any resources, I would appreciate it a lot. I have not found any online, and I have been searching for a while.

Thanks!


Best Answer:


Quinine is a natural product extracted from the bark of the cinchona tree. It was discovered to be a prophylactic against malaria. The Brits in India used it in combination with lemon juice, sugar and soda water to make tonic water, which helps reduce your chances of catching malaria there. The bitter taste gives tonic water a pleasant flavour. Chloroquine is chemically similar, more effective and completely synthetic.
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What are different types of drugs that are used for leukemia?… by Tab

April 23, 2007 · Filed Under etoposide · Comment 

Hi, I was curious about leukemia and was wondering what are drugs that are used for it? Thanks!!!


Best Answer:


Depends on the type of leukemia, but here are some used in treating Acute Lymphoblastic Leukemia: Cytoxan, Daunorubicin, Cytarabine, 6-mercaptopurine, Methotrexate, Etoposide, Vincristine, Prednisone, Dexamethasone, Asparaginase…
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What does acetaminophen cause when given to CF patients?… by sara

April 21, 2007 · Filed Under equetro · Comment 

I have cystic fybrosis and my dad has told me that acetaminophen is bad for my health in the long term use. I'd really appreciate it if you'd let me know, it's much needed information. I have serached all over the net and not found one answer.


Best Answer:


Anti-inflammatory agents help reduce the destruction of lung tissue caused by the persistent infections and chronic inflammatory response associated with CF. Available therapies include corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs), cytokine inhibitors, antiproteases, and antioxidants.

Steroids may be initially given orally for varying periods of time, depending upon the patient's age and pulmonary response. Systemic steroid use in children has been associated with delayed growth. Long-term use is associated with an increased risk of diabetes and cataracts. They may also be administered parenterally during acute exacerbations. Taken regularly, oral NSAIDs have been shown to slow the decline of pulmonary function in younger patients with mild disease.

Complications resulting from high-dose NSAID treatment include stomach irritation, clotting abnormalities, and renal toxicity, particularly when these drugs are combined with nephrotoxic antibiotics. Cytokine inhibitors, antiproteases, and antioxidants are all still under investigation for their possible anti-inflammatory benefits in CF patients

Non-steroidal anti-inflammatory drugs (NSAID)

High doses, non steroidal anti-inflammatory agents such as Ibuprofen can inhibit neutrophil migration and adherence, and inhibit the release of lysosomal enzymes. In rat studies Ibuprofen has been demonstrated to significantly reduce lung inflammation. Getting the dose right is likely to be important as there is some evidence to suggest that the use of low drug concentrations could increase the influx of neutrophils into the lungs

The major disadvantage of the NSAID relates to their narrow treatment window and high side effect profile. Close monitoring of plasma levels is mandatory to ensure both a potential therapeutic effect and to prevent toxicity. Acetaminophen or Tylenol is considered a NSAID..NSAID can cause hepatotoxicity and renal toxicity, gastrointestinal bleeding (GI) gastrci erosion; and has been linked to Hypertension and even Cancer.

Because you need this drug to reduce the inflammation and for pain relief; it's a good idea to take it with food and a glass of water to prevent the side effects.

Nonsteroidal anti-inflammatory drugs for cystic fibrosis

Examples
ibuprofen (Advil, Motrin)

How It Works

Nonsteroidal anti-inflammatory drugs (NSAIDs) reduce inflammation and pain. Always take these medicines exactly as directed.

Why It Is Used

People who have cystic fibrosis often have continued lung inflammation from frequent infections. This inflammation can lead to lung damage that makes it harder to fight infection. NSAIDs help reduce inflammation in some people who have cystic fibrosis.

Reasons not to take NSAIDs
Do not take NSAIDs if you have ever had an allergic reaction to any type of pain medicine.

If you are pregnant, trying to become pregnant, or breast-feeding, talk to your doctor before you use NSAIDs. It is especially important to avoid using NSAIDs during the last 3 months of pregnancy unless your doctor tells you to do so. They can cause problems with the baby or the delivery.

Talk to your doctor before taking NSAIDs if you have:

Ulcers or a history of stomach or intestinal bleeding.
Stomach pain, upset stomach, or heartburn that lasts or comes back.
Anemia.
Bleeding problems.
A habit of drinking more than 3 alcoholic drinks a day. This increases your risk of stomach bleeding.
High blood pressure.
Kidney, liver, or heart disease.
Any serious health condition.
Talk to your doctor before using NSAIDs if you take:

Talk to your doctor before using NSAIDs if you take:

Blood thinners (anticoagulants).
Lithium.
Diuretics (water pills).
Medicine for arthritis or diabetes.
Any other drugs.

Ibuprofen is the only NSAID that has been studied as a treatment for people with cystic fibrosis. In some children, ibuprofen can significantly slow the progression of lung disease, improve breathing, and help maintain body weight.

Side Effects

The most common side effects of NSAIDs are stomach upset, heartburn, and nausea. To help prevent these side effects, take NSAIDs with food and a glass of water.
NSAIDs can cause a severe allergic reaction. Symptoms may include hives, swelling of the face, wheezing, and shock. If you have any of these symptoms, call 911 or other emergency services immediately.
Long-term use of NSAIDs may cause ulcers and high blood pressure. Talk to your doctor about how long you should take NSAIDs.

In very rare instances, ibuprofen has caused meningitis. No one has died of this complication, but hospitalization is required to treat it. People who have an autoimmune disease, such as systemic lupus erythematosus, may be more at risk for developing meningitis

I found a lot of links on this subject matter:

Cystic fibrosis Medical Information
Cystic fibrosis Information from Drugs.com … Acetaminophen. Prevacid. Equetro. Tindamax. Lithium. Top 200 by Sales. Join Drugs.com …www.drugs.com/enc/cystic-fibrosis.html -

Cystic Fibrosis: Therapeutic Options For Co-management (PDF)
Cystic fibrosis (CF) is a cruel and deadly disease … prevention of acetaminophen-induced hepato- toxicity by N-acetyl-L-cysteine in vivo: Studies …www.thorne.com/media/cysticfibrosis.pdf - 95k - View as html -

Cystic Fibrosis | A Support Community for those dealing with Cystic …
Welcome to the community for people concerned with cystic fibrosis. … painkillers (aspirin, paracetamol (acetaminophen) or similar), inhaling steam, …wiki.cysticfibrosis.com/index.php?title=Sinusitis -

Find in a Library: Oski's pediatrics : principles & practice
… management — Salicylism — Acetaminophen overdose — Plant poisoning … Ciliary dyskinesia — Cystic fibrosis — Pulmonary hemosiderosis — Obstructive …worldcatlibraries.org/wcpa/ow/27250973aaff7deea19afeb4da09e526.html -

UAB Center for Nursing Research: Pain & Cystic Fibrosis Pharmacologic …
Aspirin and ACETAMINOPHEN (Tylenol) are two common over-the-counter pain relievers. … In many cases, aspirin or acetaminophen is all that you need to …www.cfcenter.uab.edu/paincf6/pharm.html

Aceteminophine w/Codine Sulfate and Codeine Phosphate. Acetylcysteine. Cystic Fibrosis DX only … Hydrochloride/Acetaminophen. Propulsid. Prostaphlin …www.dhss.mo.gov/shcn/

Asthma, COPD Linked to Frequent Acetaminophen Use
… found that frequent use of acetaminophen increases the risks for asthma, chronic … Smoking Asthma COPD Emphysema Cystic Fibrosis Lung Cancer Pneumonia Mesothelioma …lungdiseases.about.com/b/a/166783.htm -

Asthma, COPD Linked to Frequent Acetaminophen Use
… Smoking Asthma COPD Emphysema Cystic Fibrosis Lung Cancer Pneumonia Mesothelioma … is Empyema Thoracis?What is Cystic Fibrosis?Asthma Screening Quiz - Does Your …lungdiseases.about.com/b/a/166783.htm?terms=copd+medications -

Current Research/Innovations, Cystic Fibrosis
… Lung Disease and Pulmonary Fibrosis / AVONEX

How long can my dog live with a heart murmur?… by Becky

April 21, 2007 · Filed Under furosemide · Comment 

I took him to the vet and she said at most he will live 3 months with medication. We started the meds and he is not getting any better. I live in Spain on a military base so I can not get another opinion on his health. What should I do? Oh, he is an 11 year old beagle.
I am trying to make him as comfortable as possible and encouraging him to eat, but he seems miserable. The did not state the “grade” of the murmur but she did say that it is very, very bad.
I noticed a problem when he started loosing a lot of weight and getting lagthargic. He does not want to eat or anything.


Best Answer:


Your dog has what is called congestive heart failure. The mumur is the sound that is heard when his mitral (most likely) valve does not close properly and leaks blood back up into the left atrium (blood is going backwards instead of forewards). The extra blood in the left atrium backs up into the pulmonary vessels (lungs) and leaks fluid into the air sacks, resulting in 'water in the lungs'. The heart muscle will eventually fail because it cannot pump enough blood to the rest of the body.
Your dog is probably on furosemide, enalapril and spirinolactone. These medications are exceptionally helpfull in manageing heart failure, but can occasionally cause side effects such as anorexia and nausea (do to electrolyte abnormalities, most likely). However, anorexia can also be caused by worsening of his condition.

my advice is to call your veterinarian, or bring your dog the him/her to talk over your concerns and so that your vet can look at him again and maybe change his therapy depending on what they see.

Mitral insufficiancy in beagles (and other dogs) can be caused by valvular degeneration (most likely in your dogs case) or can be congenital. Either way, there is not a thing you could have done to prevent it, so dont beat yourself up for not having noticed it earlier.

I am sorry for you and your dog
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What is the best anti-depressant for treating depression and anxiety disorders ?… by david

April 20, 2007 · Filed Under amoxapine · Comment 

I am suffering with both anxiety and depression, what medications will help the most?


Best Answer:


Amoxapine 50 to 100 mgs. a day.Vitamin B6 50 mgs. a day.St John's Wort 300 mg.at .15% 2 times a day.Psuedophrine nasanl decongestant 60 mg. a day.Do not take the amoxapine with the St.John's Wort.Zing herbal supplement.Ginkgo Bilobka 30 mgs. a day.
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How do you treat eczma on a childs face?… by worriedm

April 19, 2007 · Filed Under elocon · Comment 

We are off to a wedding in three weeks time and our daughter has come home from school with eczma accross her face. Not the best look for a bridesmaid!!

She has had eczma since the age of three, but never on her face. I have raided the medicine chest and found that none of the steriods etc are licenced for use on the face. We have moisturised - Is there anything else we can do?
Thanks, daughter has many food allergies, hay fever and is also Coelliac - poor love. Diet seems to be well controlled at moment - she not admitted to any little slip ups (kind teachers, friends and diner ladies feel sorry for her and feed her biscuits, sweets, cakes sometimes).
PS steriods I talking about have been prescribed by her doctor for her eczma! - but instructions say not for face! Would not dream of giving unprescribed medicine to any child!


Best Answer:


Has your daughter got any food intolerances, as atopic eczema in young kids is often linked to food intolerance/allergy? I ask because my son has had lots of allergies sinces young, and always symptomises by breaking out in eczema or hives! If we keep him off suspect foods, his skin is perfect. Get her allergy-tested so she can be eczema-free in the long-run. Don't just cure the symptoms, get to the root cause.

As a short-term measure, go ask your GP to prescribe Elocon, which is a hydrocortisone cream for treating eczema. I've used it on his face - it's fine as checked with his consultant. BUT use it sparingly, and I promise, it will go away within days. Also, try moisturing with non-perfumed creams on top of the Elocon like E45. Good luck, hope it helps.
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Why are surgical infections so bad, and how are they treated?… by train

April 17, 2007 · Filed Under cubicin · Comment 

I just had knee surgery and my doctors keep checking to see if its infected. They make it sound like that would be the worst thing that could happen. How bad would this be? And how would a surgical infection be treated?


Best Answer:


try to relax.

the surgeon is just doing his job in making sure your knee heals properly and germ-free.

right now your body's immune system is compromised due to it try to heal your knee after surgery. your body is more suspectible to catching an infection right now than it normally would be and your dr just wants to make sure he stays on top of it-this is a good thing.

most people that come into the hospital and have had surgery are suseptible to drug-resistant germs. the two most common forms are MRSA (Methicillin-resistant Staphylococcus aureus ) and VRE ( Vanocomycin-resistant Enterococci ). both of these illness are hard to treat b/c they are resistant to most antibiotics.

once you have come into contact with these germs-they stay with you. The only time you can spread it to others is when the germ is “active” within your system-other times it lies dormant causing no harm. whenever you come to the hospital they will put you on what is called “contact precautions”. this means that anyone that enters your room will have to wear gloves and a special type of paper gown to prevent the germs from spreading onto their clothing and spreading to others once they leave your room. handwashing is the best prevention of spreading either germ.

to treat them-high doses of heavy duty antibioitics is given via I.V. for the MRSA-usually vancomycin is used. for the VRE-zyvox, Synercid, or Cubicin is used. these are given about every 8 hours for several days until the germ is declared no longer active in your system.

i would not be too worried about this as it sounds like your surgeon is doing an awesome job at making sure you stay healthy while your knee heals.

good luck to you
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What is the difference between Clarinex and Claritin?… by Spark

April 15, 2007 · Filed Under clarinex · Comment 

I've been taking Zyrtec and it helps me but gets me sleepy; I took Claritin when it came out and after a while did not work too good. I suffer from high blood pressure, but controlled with meds can anyone tell me the difference.


Best Answer:


The makers changed the formulation of Clarinex because they put Claritin over the counter (without prescription) Claritin contains 10 mg of Loratidine and the new formulation of Clarinex has 5 mg desloratidine. both work basically the same by inhibiting hystamine receptors so that your body does not release hystamine in response to alergens. Most insurance companies will not cover Clarinex without prior authorization due to failure of Claritin or loratidine product. Hope that helps.
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What is the difference between Diazepam and Lorazapam?… by GERALDINE

April 15, 2007 · Filed Under diazepam · Comment 

Hi could anybody tell me the difference between lorazapam and diazepam, and what can be taken with them, and the effects they have on one please?


Best Answer:


Both drugs are super addictive and produce high amounts of tolerance and severe withdrawal symptoms. The main difference between lorazepam (ativan) and diazepam (valium) is the drug half life. See this page for further information http://www.bcnc.org.uk/equivalence.html
Diazepam is often used to wean a person off of lorazepam as lorazepam is very short acting and comes in high potency tablets whereas diazepam is longer acting. 1 mg of lorazepam is equivalent to 10 mg of diazepam.
Long term use can often lead to depression, poor mental and physical health. The side effects of lorazepam, diazepam and other tranx and sleeping pills are similar to the effects of prolonged alchol over use (minus the organ damage), such as poor mental and physical health.
If you have unexplained health problems I recommend that you look further into your pills and research them more. http://www.bcnc.org.uk and http://www.benzo.org.uk/manual/ are good starters.
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