Do you know if a person can take to much dilantin?… by cliffredang
Maybe overdose is not the right word. Let us say take to much & the side effects.
Best Answer:
What are the possible side effects of phenytoin?
If you experience any of the following serious side effects, stop taking phenytoin and seek emergency medical attention or contact your doctor immediately:
an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
hallucinations;
slurred speech or staggering walk;
a rash;
changes in vision;
agitation;
low blood pressure;
slow or irregular heartbeats;
abdominal pain, dark urine, light colored stools, or jaundice (yellow skin or eyes);
easy bruising or bleeding; or
swollen or tender gums.
Other, less serious side effects may be more likely to occur. Continue to take phenytoin and talk to your doctor if you experience
nausea, vomiting, constipation, or diarrhea;
mild dizziness or drowsiness;
tender or swollen glands;
swollen or painful gums;
headache;
muscle twitches;
increased facial hair;
swelling of breasts, or
insomnia.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
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What other drugs will affect phenytoin?
The following drugs can increase the level of phenytoin in the blood which may cause dangerous side effects:
alcohol (with occasional use);
other seizure medicines such as ethosuximide (Zarontin) or methsuximide (Celontin Kapseals);
the stomach medicines cimetidine (Tagamet, Tagamet HB) or ranitidine (Zantac, Zantac 75);
the anxiety and insomnia medicines chlordiazepoxide (Librium, Librax) and diazepam (Valium);
estrogens such as conjugated estrogens (Premarin, Premphase, Prempro), estradiol (Estrace), esterified estrogens (Estratab, Menest), estropipate (Ogen), and estrogen patches (Estraderm, Vivelle, Climara);
the heart medicine amiodarone (Cordarone);
salicylates such as aspirin, magnesium salicylate (Magan), choline salicylate (Arthropan), and choline and magnesium salicylate (Trilisate);
anti-infective medicines such as isoniazid (Nydrazid) and sulfonamides such as sulfamethoxazole (Septra, Bactrim);
methylphenidate (Ritalin, Concerta, Metadate, Methylin);
tolbutamide;
trazodone (Desyrel); and
disulfiram (Antabuse).
Other drugs may decrease the amount of phenytoin in the blood. This can decrease the effects of phenytoin and result in seizures. The following drugs may have this effect:
alcohol (when used regularly);
carbamazepine (Tegretol, Epitol, Carbatrol);
reserpine;
sucralfate (Carafate); and
molindone (Moban).
Other seizure medicines may interact unpredictably with phenytoin and either increase or decrease its effects. These drugs include
valproic acid (Depakene) and divalproex sodium (Depakote); and
phenobarbital (Luminal).
It may be necessary for your doctor to adjust your phenytoin dosage if you are taking any of the medicines listed above.
Phenytoin may also decrease the activity of other medicines, including
steroid medicines such as prednisone (Deltasone), hydrocortisone (Cortef), betamethasone (Celestone), dexamethasone (Decadron), methylprednisolone (Medrol), and others;
warfarin (Coumadin);
quinidine (Quinidex, Quinaglute, others);
birth control pills;
estrogens such as Premarin, Ogen, Menest, Estratest, Estraderm, Vivelle, Climara, and others;
the anti-infective medicines rifampin (Rimactane, Rifadin) and doxycycline (Doryx, Vibramycin, Doxy, Monodox, Adoxa, others);
furosemide (Lasix); and
theophylline (Theo-Dur, Theochron, Theo-Bid, Theolair, Aerolate, others).
Drugs other than those listed here may also interact with phenytoin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.
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Where can I get more information?
Your pharmacist has additional information about phenytoin written for health professionals that you may read.
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